Our companies solve hard but not impossible problems.
4
Funds raised
$50M
Current fund
$1-2M
Typical check
10%
Target ownership
Our Portfolio
Discover the companies shaping the future with Refactor.
Aerospace
Biotech
Verge uses ML and genomics to tackle neurodegenerative diseases.
64x is transforming the future of cell and gene therapy manufacturing.
Juvena develops therapeutics for tissue regeneration.
Rubedo is an anti-aging company hoping to extend health-span.
Gencove's low-pass sequencing is the most efficient for genomic discovery.
Shape is a next-gen RNA-targeting gene therapy company.
Loyal is giving our best friends (our dogs) more time with us.
Octant is building a novel drug discovery platform.
Mythic is building smarter and safer anti-drug conjugates.
YourChoice is developing the pill for men.
Miist develops orally inhaled therapeutics.
Parallel Bio uses immune organoids to design drugs.
Adventris makes cancer vaccines.
Granza is advancing therapeutic delivery using precision shells.
Vitra is reimagining IVF.
Reel is scaling its vascularization technology to support therapeutics.
Phytoform edits crop genomes to activate novel traits.
BBB trains AI models using biology.
Pilgrim develops battlefield-ready technology.
Biorender is redefining how science is communicated.
Critical Materials
Checkerspot builds sustainable, algae-based physical materials.
Intropic designs self-degradable products.
Macro Oceans transforms kelp into chemicals.
Hyfé turns plant waste into chemicals.
Aether manufactures enzymes for novel products.
Culture accelerates biomanufacturing.
Solugen manufactures chemicals using biology.
FYTO is building sustainable, novel nutrient-dense crops.
Berkeley Yeast engineers brewer’s yeast to do incredible things.
Knowde is bringing the chemical industry online.
Energy/Geo
General Galactic creates fossil-free fuels and chemicals.
Lumindt is building solid-state stationary storage systems.
Network Ocean builds underwater data centers.
Thalo helps reduce energy costs and emissions.
Pila is the simplest, smartest home backup battery.
Causal is building AI physics models to predict and control the weather.
Floodbase is a global parametric flood insurance solution.
Remedy is bringing land back online.
Hexium enriches isotopes for nuclear energy.
Health
PathAI is advancing medicine with intelligent pathology.
Headspace teaches millions in 200+ countries how to live mindfully.
Picnic structures the world's medical data and makes it useful.
Lucy’s aim is to eliminate smoking via effective nicotine products.
Ophelia provides medication & support for quitting opioids.
Vital is modern emergency department software.
AKASA is modernizing revenue cycle operations for healthcare.
Curative is building a new employer health plan.
Orchid helps couples have healthy babies.
Kin creates functional beverages.
Biobot analyzes wastewater to analyze population threats.
Stealth
Graduates
Coinbase is a cryptocurrency exchange and went public ($COIN).
Able helps providers get paid and was acquired by Health Catalyst ($HCAT).
ANA is fighting COVID and was acquired by Neurobo ($NRBO).
Blockfolio is a crypto wallet and was acquired by FTX.
Umbrella is a senior care marketplace and was acquired ($IAC).
Betty Labs built Locker Room and was acquired by Spotify ($SPOT).
Clover is a Medicare Advantage company and went public ($CLOV).
Kip is a mental health company and was acquired by Modern Health.
Hero is a CRM app and was acquired by People.AI.
FactoryFour builds automation software and was acquired by Xometry ($XMTR).
Tempest is a digital recovery program and was acquired by Monument.
Enzyme is FDA compliance as a service and was acquired by Roivant ($ROIV).
Uniform is a tele-health orthodontics company and was acquired by Impress Dental.
Avail provides virtual surgery consults and was acquired by Mendaera.