Our companies solve hard but not impossible problems.
4
Funds raised
$50M
Current fund
$1-2M
Typical check
10%
Target ownership
Our Portfolio
Discover the companies shaping the future with Refactor.
Aerospace
Biotech

Shape is a next-gen RNA-targeting gene therapy company.

Verge uses ML and genomics to tackle neurodegenerative diseases.

Gencove's low-pass sequencing is the most efficient for genomic discovery.

BBB trains AI models using biology.

Adventris makes cancer vaccines.

Juvena develops therapeutics for tissue regeneration.

Mythic is building smarter and safer anti-drug conjugates.

Rubedo is an anti-aging company hoping to extend health-span.

Miist develops orally inhaled therapeutics.

Phytoform edits crop genomes to activate novel traits.

Reel is scaling its vascularization technology to support therapeutics.

Granza is advancing therapeutic delivery using precision shells.

Parallel Bio uses immune organoids to design drugs.

Loyal is giving our best friends (our dogs) more time with us.

YourChoice is developing the pill for men.

Vitra is reimagining IVF.

64x is transforming the future of cell and gene therapy manufacturing.

Octant is building a novel drug discovery platform.
Critical Materials

Culture accelerates biomanufacturing.

Aether manufactures enzymes for novel products.

Hyfé turns plant waste into chemicals.

Macro Oceans transforms kelp into chemicals.

Solugen manufactures chemicals using biology.

FYTO is building sustainable, novel nutrient-dense crops.

Checkerspot builds sustainable, algae-based physical materials.

Berkeley Yeast engineers brewer’s yeast to do incredible things.

Intropic designs self-degradable products.
Energy
Health

Ophelia provides medication & support for quitting opioids.

PathAI is advancing medicine with intelligent pathology.

Vital is modern emergency department software.

Curative is building a new employer health plan.

Kin creates functional beverages.

Picnic structures the world's medical data and makes it useful.

Orchid helps couples have healthy babies.

Biobot analyzes wastewater to analyze population threats.

Headspace teaches millions in 200+ countries how to live mindfully.

AKASA is modernizing revenue cycle operations for healthcare.

Lucy’s aim is to eliminate smoking via effective nicotine products.
Software
Stealth
Graduates

Kip is a mental health company and was acquired by Modern Health.

Able helps providers get paid and was acquired by Health Catalyst ($HCAT).

Clover is a Medicare Advantage company and went public ($CLOV).

Betty Labs built Locker Room and was acquired by Spotify ($SPOT).

FactoryFour builds automation software and was acquired by Xometry ($XMTR).

Blockfolio is a crypto wallet and was acquired by FTX.

Hero is a CRM app and was acquired by People.AI.

ANA is fighting COVID and was acquired by Neurobo ($NRBO).

Avail provides virtual surgery consults and was acquired by Mendaera.

Umbrella is a senior care marketplace and was acquired ($IAC).

Tempest is a digital recovery program and was acquired by Monument.

Enzyme is FDA compliance as a service and was acquired by Roivant ($ROIV).

Coinbase is a cryptocurrency exchange and went public ($COIN).

Uniform is a tele-health orthodontics company and was acquired by Impress Dental.