Our companies solve hard but not impossible problems.
4
Funds raised
$50M
Current fund
$1-2M
Typical check
10%
Target ownership
Our Portfolio
Discover the companies shaping the future with Refactor.
Aerospace
Biotech
Miist develops orally inhaled therapeutics.
Biorender is redefining how science is communicated.
YourChoice is developing the pill for men.
Gencove's low-pass sequencing is the most efficient for genomic discovery.
Granza is advancing therapeutic delivery using precision shells.
Epana is using AI to build autoimmune therapeutics.
Pilgrim develops battlefield-ready technology.
Parallel Bio uses immune organoids to design drugs.
Adventris develops off-the-shelf cancer therapies.
Mythic is building smarter and safer anti-drug conjugates.
BBB trains AI models using biology.
Vitra is reimagining IVF.
64x is transforming the future of cell and gene therapy manufacturing.
Phytoform edits crop genomes to activate novel traits.
Loyal is giving our best friends (our dogs) more time with us.
Octant is building a novel drug discovery platform.
Critical Materials
Knowde is bringing the chemical industry online.
Aether manufactures enzymes for novel products.
Checkerspot builds sustainable, algae-based physical materials.
Solugen manufactures chemicals using biology.
Berkeley Yeast engineers brewer’s yeast to do incredible things.
Macro Oceans transforms kelp into chemicals.
FYTO is building sustainable, novel nutrient-dense crops.
Earth Systems
Energy
Health
Kin creates functional beverages.
AKASA is modernizing revenue cycle operations for healthcare.
Curative is building a new employer health plan.
PathAI is advancing medicine with intelligent pathology.
Ophelia provides medication & support for quitting opioids.
Picnic structures the world's medical data and makes it useful.
Lucy’s aim is to eliminate smoking via effective nicotine products.
Atlas unlocks a deeper understanding of your mind.
Vital is modern emergency department software.
Headspace teaches millions in 200+ countries how to live mindfully.
Orchid helps couples have healthy babies.
Stealth
Graduates
ANA is fighting COVID and was acquired by Neurobo ($NRBO).
Blockfolio is a crypto wallet and was acquired by FTX.
Umbrella is a senior care marketplace and was acquired ($IAC).
Coinbase is a cryptocurrency exchange and went public ($COIN).
Avail provides virtual surgery consults and was acquired by Mendaera.
Betty Labs built Locker Room and was acquired by Spotify ($SPOT).
FactoryFour builds automation software and was acquired by Xometry ($XMTR).
Clover is a Medicare Advantage company and went public ($CLOV).
Kip is a mental health company and was acquired by Modern Health.
Hero is a CRM app and was acquired by People.AI.
Tempest is a digital recovery program and was acquired by Monument.
Able helps providers get paid and was acquired by Health Catalyst ($HCAT).
Enzyme is FDA compliance as a service and was acquired by Roivant ($ROIV).
Uniform is a tele-health orthodontics company and was acquired by Impress Dental.