Our companies solve hard but not impossible problems.
4
Funds raised
$50M
Current fund
$1-2M
Typical check
10%
Target ownership
Our Portfolio
Discover the companies shaping the future with Refactor.
Aerospace
Biotech
Phytoform edits crop genomes to activate novel traits.
64x is transforming the future of cell and gene therapy manufacturing.
YourChoice is developing the pill for men.
Loyal is giving our best friends (our dogs) more time with us.
BBB trains AI models using biology.
Mythic is building smarter and safer anti-drug conjugates.
Epana is using AI to build autoimmune therapeutics.
Granza is advancing therapeutic delivery using precision shells.
Octant is building a novel drug discovery platform.
Gencove's low-pass sequencing is the most efficient for genomic discovery.
Vitra is reimagining IVF.
Miist develops orally inhaled therapeutics.
Pilgrim develops battlefield-ready technology.
Biorender is redefining how science is communicated.
Parallel Bio uses immune organoids to design drugs.
Adventris develops off-the-shelf cancer therapies.
Critical Materials
Aether manufactures enzymes for novel products.
FYTO is building sustainable, novel nutrient-dense crops.
Berkeley Yeast engineers brewer’s yeast to do incredible things.
Solugen manufactures chemicals using biology.
Macro Oceans transforms kelp into chemicals.
Knowde is bringing the chemical industry online.
Checkerspot builds sustainable, algae-based physical materials.
Earth Systems
Energy
Health
Atlas unlocks a deeper understanding of your mind.
Kin creates functional beverages.
Vital is modern emergency department software.
Orchid helps couples have healthy babies.
Headspace teaches millions in 200+ countries how to live mindfully.
Picnic structures the world's medical data and makes it useful.
AKASA is modernizing revenue cycle operations for healthcare.
Curative is building a new employer health plan.
Lucy’s aim is to eliminate smoking via effective nicotine products.
PathAI is advancing medicine with intelligent pathology.
Ophelia provides medication & support for quitting opioids.
Stealth
Graduates
Hero is a CRM app and was acquired by People.AI.
Blockfolio is a crypto wallet and was acquired by FTX.
Avail provides virtual surgery consults and was acquired by Mendaera.
Able helps providers get paid and was acquired by Health Catalyst ($HCAT).
ANA is fighting COVID and was acquired by Neurobo ($NRBO).
Uniform is a tele-health orthodontics company and was acquired by Impress Dental.
FactoryFour builds automation software and was acquired by Xometry ($XMTR).
Clover is a Medicare Advantage company and went public ($CLOV).
Coinbase is a cryptocurrency exchange and went public ($COIN).
Betty Labs built Locker Room and was acquired by Spotify ($SPOT).
Enzyme is FDA compliance as a service and was acquired by Roivant ($ROIV).
Umbrella is a senior care marketplace and was acquired ($IAC).
Kip is a mental health company and was acquired by Modern Health.
Tempest is a digital recovery program and was acquired by Monument.