Our companies solve hard but not impossible problems.
4
Funds raised
$50M
Current fund
$1-2M
Typical check
10%
Target ownership
Our Portfolio
Discover the companies shaping the future with Refactor.
Hard Tech - Industrials
FYTO is building sustainable, novel nutrient-dense crops.
Phytoform edits the genomes of crops to activate novel traits.
Berkeley Yeast engineers brewer’s yeast to do incredible things.
Solugen uses biology to build chemicals.
Checkerspot builds sustainable, algae-based physical materials.
Macro Oceans transforms seaweed into low-carbon chemicals.
Thalo measures and mitigates greenhouse gas emissions in the built environment.
Hyfé transforms wastewater into valuable products.
Reel is creating 100% cell-based seafood.
Lumindt is building solid-state stationary storage systems.
Intropic is creating truly compostable and self-degrading products.
Bedrock Materials is building low-cost sodium ion batteries.
General Galactic creates fossil-free fuels and chemicals.
Network Ocean builds underwater data centers.
Astranis is building the world's most advanced high-orbit satellites.
Biology
Biorender is redefining how science is communicated.
Verge uses ML and genomics to tackle neurodegenerative diseases.
Culture is building the future of biomanufacturing.
64x is transforming the future of cell and gene therapy manufacturing.
Aether is a computational enzyme discovery platform.
Juvena develops therapeutics for tissue regeneration.
Curative is scaling COVID-19 detection and vaccination.
Kin has created a whole new category of beverages called euphorics.
Biobot measures opioids and COVID-19 in sewer water.
Rubedo is an anti-aging company hoping to extend health-span.
Gencove's low-pass sequencing is the most efficient for genomic discovery.
Shape is a next-gen RNA-targeting gene therapy company.
Orchid helps couples have the healthiest children possible.
Loyal is giving our best friends (our dogs) more time with us.
Octant is building a novel drug discovery platform.
Mythic is building smarter and safer anti-drug conjugates.
YourChoice is developing the pill for men.
Miist develops orally inhaled therapeutics.
Parallel Bio uses immune organoids to design drugs.
Adventris is building new cancer immunotherapies.
Granza is advancing therapeutic delivery using precision shells.
Software - Industrials
Health
PathAI is advancing medicine with intelligent pathology.
Headspace teaches millions in 200+ countries how to live mindfully.
Picnic structures the world's medical data and makes it useful.
Lucy’s aim is to eliminate smoking via effective nicotine products.
Ophelia provides medication & support for quitting opioids.
Vital is modern emergency department software.
AKASA is modernizing revenue cycle operations for healthcare.
Graduates
Coinbase is a cryptocurrency exchange and went public ($COIN).
Able helps providers get paid and was acquired by Health Catalyst ($HCAT).
ANA is fighting COVID and was acquired by Neurobo ($NRBO).
Blockfolio is a crypto wallet and was acquired by FTX.
Umbrella is a senior care marketplace and was acquired ($IAC).
Betty Labs built Locker Room and was acquired by Spotify ($SPOT).
Clover is a Medicare Advantage company and went public ($CLOV).
Kip is a mental health company and was acquired by Modern Health.
Hero is a CRM app and was acquired by People.AI.
FactoryFour builds automation software and was acquired by Xometry ($XMTR).
Tempest is a digital recovery program and was acquired by Monument.
Enzyme is FDA compliance as a service and was acquired by Roivant ($ROIV).
Uniform is a tele-health orthodontics company and was acquired by Impress Dental.
Avail provides virtual surgery consults and was acquired by Mendaera.