Our companies solve hard but not impossible problems.
4
Funds raised
$50M
Current fund
$1-2M
Typical check
10%
Target ownership
Our Portfolio
Discover the companies shaping the future with Refactor.
Aerospace
Biotech
Parallel Bio uses immune organoids to design drugs.
Adventris develops off-the-shelf cancer therapies.
Gencove's low-pass sequencing is the most efficient for genomic discovery.
Mythic is building smarter and safer anti-drug conjugates.
Epana is using AI to build autoimmune therapeutics.
Pilgrim develops battlefield-ready technology.
Miist develops orally inhaled therapeutics.
Octant is building a novel drug discovery platform.
Biorender is redefining how science is communicated.
BBB trains AI models using biology.
Granza is advancing therapeutic delivery using precision shells.
Vitra is reimagining IVF.
64x is transforming the future of cell and gene therapy manufacturing.
YourChoice is developing the pill for men.
Loyal is giving our best friends (our dogs) more time with us.
Phytoform edits crop genomes to activate novel traits.
Critical Materials
Knowde is bringing the chemical industry online.
Aether manufactures enzymes for novel products.
Macro Oceans transforms kelp into chemicals.
FYTO is building sustainable, novel nutrient-dense crops.
Berkeley Yeast engineers brewer’s yeast to do incredible things.
Checkerspot builds sustainable, algae-based physical materials.
Solugen manufactures chemicals using biology.
Earth Systems
Energy
Health
Ophelia provides medication & support for quitting opioids.
Vital is modern emergency department software.
AKASA is modernizing revenue cycle operations for healthcare.
Lucy’s aim is to eliminate smoking via effective nicotine products.
Picnic structures the world's medical data and makes it useful.
PathAI is advancing medicine with intelligent pathology.
Atlas unlocks a deeper understanding of your mind.
Orchid helps couples have healthy babies.
Kin creates functional beverages.
Headspace teaches millions in 200+ countries how to live mindfully.
Curative is building a new employer health plan.
Stealth
Graduates
Umbrella is a senior care marketplace and was acquired ($IAC).
Coinbase is a cryptocurrency exchange and went public ($COIN).
Avail provides virtual surgery consults and was acquired by Mendaera.
Kip is a mental health company and was acquired by Modern Health.
Able helps providers get paid and was acquired by Health Catalyst ($HCAT).
FactoryFour builds automation software and was acquired by Xometry ($XMTR).
ANA is fighting COVID and was acquired by Neurobo ($NRBO).
Hero is a CRM app and was acquired by People.AI.
Uniform is a tele-health orthodontics company and was acquired by Impress Dental.
Enzyme is FDA compliance as a service and was acquired by Roivant ($ROIV).
Blockfolio is a crypto wallet and was acquired by FTX.
Tempest is a digital recovery program and was acquired by Monument.
Betty Labs built Locker Room and was acquired by Spotify ($SPOT).
Clover is a Medicare Advantage company and went public ($CLOV).