Our companies solve hard but not impossible problems.
4
Funds raised
$50M
Current fund
$1-2M
Typical check
10%
Target ownership
Our Portfolio
Discover the companies shaping the future with Refactor.
Aerospace
Biotech

YourChoice is developing the pill for men.

Parallel Bio uses immune organoids to design drugs.

Gencove's low-pass sequencing is the most efficient for genomic discovery.

Octant is building a novel drug discovery platform.

Mythic is building smarter and safer anti-drug conjugates.

Adventris develops off-the-shelf cancer therapies.

Pilgrim develops battlefield-ready technology.

Biorender is redefining how science is communicated.

Granza is advancing therapeutic delivery using precision shells.

BBB trains AI models using biology.

64x is transforming the future of cell and gene therapy manufacturing.

Phytoform edits crop genomes to activate novel traits.

Epana is using AI to build autoimmune therapeutics.

Loyal is giving our best friends (our dogs) more time with us.

Vitra is reimagining IVF.

Miist develops orally inhaled therapeutics.
Critical Materials

Macro Oceans transforms kelp into chemicals.

Solugen manufactures chemicals using biology.

Aether manufactures enzymes for novel products.

Checkerspot builds sustainable, algae-based physical materials.

Berkeley Yeast engineers brewer’s yeast to do incredible things.

FYTO is building sustainable, novel nutrient-dense crops.

Knowde is bringing the chemical industry online.
Earth Systems
Energy
Health

Kin creates functional beverages.

Vital is modern emergency department software.

Ophelia provides medication & support for quitting opioids.

PathAI is advancing medicine with intelligent pathology.

AKASA is modernizing revenue cycle operations for healthcare.

Picnic structures the world's medical data and makes it useful.

Orchid helps couples have healthy babies.

Curative is building a new employer health plan.

Lucy’s aim is to eliminate smoking via effective nicotine products.

Headspace teaches millions in 200+ countries how to live mindfully.
Stealth
Graduates

ANA is fighting COVID and was acquired by Neurobo ($NRBO).

Enzyme is FDA compliance as a service and was acquired by Roivant ($ROIV).

Blockfolio is a crypto wallet and was acquired by FTX.

FactoryFour builds automation software and was acquired by Xometry ($XMTR).

Uniform is a tele-health orthodontics company and was acquired by Impress Dental.

Hero is a CRM app and was acquired by People.AI.

Umbrella is a senior care marketplace and was acquired ($IAC).

Coinbase is a cryptocurrency exchange and went public ($COIN).

Clover is a Medicare Advantage company and went public ($CLOV).

Tempest is a digital recovery program and was acquired by Monument.

Betty Labs built Locker Room and was acquired by Spotify ($SPOT).

Avail provides virtual surgery consults and was acquired by Mendaera.

Able helps providers get paid and was acquired by Health Catalyst ($HCAT).

Kip is a mental health company and was acquired by Modern Health.